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This population feature helped us to capture some inherited genetic differences that might be modifying the toxic effect of chronic Hg exposure

Additionally, due to the autoimmune attack and destruction of the thyroid, self-reactive antibodies such as thyroid peroxidase (TPOAb) and thyroglobulin antibodies (TgAb) become elevated and contribute to these symptoms

There is increasing evidence that these models share pathologic and biochemical characteristics seen in the more traditional models of focal and diffuse TBI, including hemorrhage, diffuse axonal injury, cortical and subcortical cell injury, metabolic disturbances/energy failure, inflammation, and oxidative stress

DSIP is studied within integrated models exploring how modulation of one domain influences the others