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Abbreviations: AM (alveolar macrophage), BAL (bronchoalveolar lavage), DC (dendritic cell), e-cig (e-cigarette), e-cig vaped extract (EVE), gen (generation), h (hour), min (minute), NK (natural killer), PG (propylene glycol), THC (tetrahydrocannabinol), VG (vegetable glycerin) Acknowledgements: The authors thank the sponsors of research in the Crotty Alexander laboratory, including the NIH (R01 HL147326, R01 HL137052, and K24 HL155884), VA (Merit 1I01BX004767, Merit 1I01BX006447), and California state funding program: Tobacco Related Disease Research Program (TRDRP

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