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2 IV Acetadote protects liver cells in 2 ways: It helps replenish glutathione It binds to and removes NAPQI Return to top The maximum adult therapeutic dose of acetaminophen is 4 grams/24 hours 3 The maximum dose for children less than 12 years is 75 mg/kg 4 Acute overdose is defined as ingestion of 150 mg/kg or 12 grams/24 hours 4 Four stages of acetaminophen overdose 5 Return to top When time is liver, timing is critical Treatment Recommendations The following recommendations are related to acute acetaminophen ingestion

All the dosing info online is from clinical experience, animal studies, or compounding pharmacy suggestions

Most vials contain 2 mg (2,000 mcg) of DSIP, and if you reconstitute with 2 mL of bacteriostatic water, you get a concentration of 1,000 mcg/mL (or 1 mcg per 0.001 mL)

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