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Tesamorelin's Phase 3 trials and Sermorelin's original approval studies were built around HIV-associated lipodystrophy and pediatric growth failure, not muscle building, so their bodybuilding use rests on extrapolation rather than direct testing

Gene Ther 2001;8:13436

Mapping each compound to its actual research context prevents the most common category error treating them as interchangeable fat-loss shots. The table below shows that they anchor to different indications and different evidence tiers

Extended transmediastinal dissection with complete sac excision is mandatory to release axial tension and to reduce at least 3 cm of distal esophagus into the abdomen