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MGF and Muscle Repair Contradictory Data A study by two pharmaceutical companies attempting to reproduce claimed satellite cell proliferation effects found that concentrations of MGF peptide up to 500 ng/ml failed to increase the proliferation of C2C12 cells or primary human skeletal muscle myoblasts while all cell types exhibited a proliferative response to mature IGF-1 or full-length IGF-1Eb calling into question whether discrete MGF peptide has a physiological role in this process and highlighting the importance of cell type, model system, and peptide formulation in MGF research design

Int J Cancer 146(6):17001716

Chronobiol Int 38(2):168181

To view or add a comment, sign in From the latest issue: Oliveira and colleagues review the emerging role of #ARBs in #Marfan syndrome, highlighting how losartan and its metabolites may modulate TGF- signaling, improve endothelial function, and slow aortic root dilation