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Mice and rats were placed on a 37 C heating pad for the duration of measurement, platinum electrodes were placed on the corneal surface, and a reference electrode was placed subcutaneously on the scalp between the eyes and a ground electrode was placed into the tail of mice and rats

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More studies are necessary to determine what factors may underlie the link

Disruption of cysteine uptake and collapse of intracellular GSH pool induces an inhibition of the detoxifying activity of GPx4 and excessive accumulation of oxidatively damaged lipids at the membrane, although it remains unclear if this solely affects the cell plasma membrane, or the effect also extends to organelle membranes