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One way to think about the difference between 10-year and lifetime risk calculators is this: imagine you are driving towards a cliff edge

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Chlorogenic Acid Lactones: What they are: Chlorogenic acid lactones (CGL) are bitter compounds with antioxidant capacity created during the coffee roasting process from dehydration of chlorogenic acids (CGA).The maximum amount of CGL represents approximately 30% of the available original CGA amount (Farah, 2005)