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Athough annotated plant GPXs use TRXs more efficiently than GSH, at least two other types of enzyme could be important in peroxidation of glutathione (Figure 6)

This correction minimizes background interference and ensures reliable quantitative comparisons between samples

their electrophilic chemistry and rapid reactivity limit systemic use at present but they define a potent downstream entry point for ferroptosis (85, 86)

Rather, they may serve as an additional tool for patients who have reached a weight loss plateau despite adherence to dietary guidelines and physical activity recommendations, or for those experiencing clinically significant weight regain that threatens their metabolic health improvements