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The CagriSema program, combining cagrilintide with semaglutide, has demonstrated: 15.1% mean body weight reduction at 32 weeks in REDEFINE 1 trial Approximately 15-17% weight loss in various phase 3 timepoints Superior outcomes compared to semaglutide monotherapy Manageable safety profile with expected GI side effects Cagrilintide 10mg remains an important research tool for scientists exploring amylin analogue applications

Purity 99% (HPLC)

Other GLP-1 and dual-agonist agents, including tirzepatide, are also in wide use, though not every GLP-1 on the market carries an FDA weight loss indication

Treatment begins at 0.25 mg semaglutide combined with a proportional cagrilintide dose, with increases occurring every four weeks