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These agents represent novel approaches in overcoming limitations of traditional antifungals, particularly in addressing resistance and improving patient compliance

How should this patient be treated

To summarise, normally occurring reactive astrogliosis is in the first instance an intrinsic and evolutionary conserved set of diverse astrocyte responses that are aimed at neuroprotection, maintenance of tissue homoeostasis and preservation of nervous tissue integrity

One study investigated the effect of oral intake of fruit extracts in combination with vitamin E and carotenoids on repigmentation in patients with vitiligo after phototherapy [133]