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In one of the studies, patients with a mean baseline body mass index (BMI) of 35.3 kg/m and an average HbA1c of 8.3% were randomized to receive varying doses of GLP-3 (ranging from 1 mg to 12 mg) or placebo over a 36-week study period

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This is one of the reasons proper dosing matters, as higher doses tend to produce more significant lipid improvements