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The computers grouped the sequences into about 20 distinct categories, or mutational signatures. Mutations tied to five of these signatures were more common in tumors from smokers than in tumors from nonsmokers

They are designed to help smokers switch from cigarettes, so the e-liquid has nicotine in as well as flavouring to give the vapour either a tobacco taste or other more varied flavours

Trying to kick the habit can be difficult

To institutionalize smoking in public places, China Tobacco has stepped up to fund the construction of thousands of smoking areas in government buildings, shopping malls, parks and other locations