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Furthermore, the DTI metrics that are used as proxies of myelin integrity do not specifically identify myelin abnormalities, but detect differences in water diffusiona parameter that can be altered by axon packing density, axon caliber, and more confounding factors (Chang et al., 2017)

They can detect peptides at concentrations in the nanogram per milliliter range or lower

The ongoing development and increased availability of DNA sequencing technology have uncovered several molecular causes of SLOCA besides spastic paraplegia type 7 and very late-onset Friedreich ataxia

1 Depending on the underlying condition, vertigo and dizziness can present in a variety of ways (see Table 1)