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As expected, since MTT and CTG assays measure cellular metabolism, the CC 50 values of both compounds were somehow lower in the various cell types as compared to growth curve assessment

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It did not affect T cell uptake due to compensatory upregulation of the glutamine transporter SLC6A14 in CD8 + T cells, which increased CD8 + T cell activation and glutathione synthesis (Edwards et al., 2021)