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There is no, no reason for that. (Aspreys wife disagrees.) All this self-experimentation is not without risk

Serious but rare complications: Hypokalaemia: Rapid B12 replacement in severely deficient patients can precipitate potassium depletion during haematopoietic recovery, potentially causing cardiac arrhythmias

However, if there are neurological symptoms that have arisen due to B12 deficiency, they could take up to three months to improve, with mild improvements occurring in the first six weeks

they are intricately involved in maintaining the health and proper functioning of the nervous system, crucial metabolic processes, and the production of red blood cells