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of State Thomas Jefferson) MADISONS (58A: "Father of the Constitution" and his family) NAVAL (60A: Like the Revolutionary War battles led by John Paul Jones) JOHN HANCOCK (64A: First signer of the Declaration of Independence) COLONY (73A: American settlement until 1776

These differences may be a dosing effect, as suggested by a study where one puff per minute exposure for 20 min did not induce neutrophilic infiltration in the lungs of mice, while four puffs per minute for the same duration did [29]

COPD among women is rising more quickly than among men, and since 2000, more women than men have died each year from COPD (CDC, 2008)

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