The water-soluble heme-containing peptides obtained by proteolytic digestion of cytochrome c are the microperoxidases (MP) often used to explore aspects of the chemistry of iron porphyrins, and as mimics for some reactions catalyzed by peroxidases (Prieto et al., 2006
Chen X, Yu C, Kang R, Kroemer G, Tang D
Kahn-Krell A, Pretorius D, Guragain B, Lou X, Wei Y, Zhang J, Qiao A, Nakada Y, Kamp TJ, Ye L, Zhang J (2022) A three-dimensional culture system for generating cardiac spheroids composed of cardiomyocytes, endothelial cells, smooth-muscle cells, and cardiac fibroblasts derived from human induced-pluripotent stem cells
This dual function is important because Leu activates mTOR, a central regulator of cellular metabolism and growth