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Although its exact etiology has not yet been fully elucidated, it is accepted that the onset of UC occurs due to an inappropriate aggressive inflammatory response

It stimulates cell migration, facilitates tissue remodeling, and aids in healing damaged tissues [3, 4]

It reduces the impact of UV radiation, airborne skin pollution, and other environmental factors that accelerate aging

Accutane (Isotretinoin) is a powerful oral medication used to treat moderate to severe acne vulgaris that has not responded to other treatments, including topical and oral antibiotics, topical tretinoin, and over-the-counter products such as salicylic acid, glycolic acid, and benzoyl peroxide