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Oxidative stress Oxidative stress is a pivotal mechanism behind ECD [99, 100], consisting of an imbalance of the redox state due to reactive oxygen species (ROS) overproduction, antioxidant systems depletion, or both

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Upon binding to AO, specific interactions induced a conformational change in the aptamer to a hairpin structure, reducing the interaction between Texas-red and PDA, allowing Texas-red release and fluorescence recovery

doi: 10.1371/journal.pone.0203944