All the different attributes of plasma including the reactive oxygen and nitrogen species (RONS), electric and magnetic field, UV and VUV photons, electrons, etc
For example, human induced pluripotent stem cell (iPS cell) astrocyte studies indicate that PSEN1 mutations enhance cytokine signaling via disrupted intramembrane proteolysis, lowering the threshold for astrocyte reactivity and predisposing cells to exaggerated inflammatory responses to modest stimuli 79
N Engl J Med (2013) 368(26):25201.10.1056/NEJMcibr1303292 186 ManzelAMullerDNHaflerDAErdmanSELinkerRAKleinewietfeldM
[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Shi K.Q., Tang J.Z., Zhu X.L., Ying L., Li D.W., Gao J., Fang Y.X., Li G.L., Song Y.J., Deng Z.J., et al