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One 2017 case series from a Croatian research group reported complete fissure closure in 87% of patients within 4 weeks using 250mcg BPC-157 dissolved in saline applied twice daily

Yes, it indirectly reduces inflammation by reducing oxidative stress

The risk is greatest among infants who are fed formula low in biotin, people taking antiepileptic medications, infants with Leiners disease or people who are genetically predisposed to deficiency ( Untreated biotin deficiency can cause neurological symptoms, such as seizures, intellectual disability and loss of muscle coordination ( Deficiency has also been reported in animals fed high amounts of raw egg whites

Kusmartsev S, Dominguez-Gutierrez PR, Canales BK, Bird VG, Vieweg J, Khan SR