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In addition, over 100 neuroactive peptides (i.e., many of these are co-released along with a small-molecule) transmitters have been found and are commonly thought to have essential functions in controlling essential systems such as reproduction, development, growth, energy homeostasis, cardiovascular activity, and stress response, thus animal physiology in general [34,35]

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Critically, IGF-1 LR3 bypasses the regulatory gatekeeping function of the liver entirely

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