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Twice-daily dosing maintains stable tissue levels

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The protocols raise many issues that are subject to change as new data emerge

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The peptide structure degrades rapidly at elevated temperatures

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Arzneim Forsch Drug Res 42:211214 Moreno L, Martnez-Cuesta MA, Muedra V, Beltrn B, Esplugues J (1997) Role of the endothelium in the relaxation induced by propofol and thiopental in isolated arteries from man

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