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As it was noted at the beginning, HOTYR is considered by far the main simple phenolic compound of table olives ( Absorption and Bioavailability The term bioavailability is commonly used to indicate the proportion of a substance that reaches the systemic circulation after oral administration considering both its absorption and its local metabolic transformation

This would be reminiscent of what is occurring in ALS patient spinal cord motor neurons with loss of cuproprotein function and thus overall function that precedes the eventual death of the neurons themselves (Hilton et al., 2024

In the absence of this enzyme, instability may occur in the midpiece of the spermatozoa, and defects in sperm motility may occur due to this instability

Cost is another factor to consider