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Mitchell, the study's senior author and a professor of medicine, epidemiology and public health at the University of Maryland School of Medicine, said in a prepared statement

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Affects the body's healing response Smoking also exhausts cellular defense and repair systems in the skin leading to an imbalance between synthesis and destruction of proteins

While GOT1/2 DKO sensor cells are maintained in 2040 mM aspartate to maximally support cell proliferation, in agreement with previously measured parameters for non-specific aspartate uptake 16,3,5,12,22 , titrating medium aspartate dose-dependently reduced their proliferation rate (Extended Data Fig