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Though it was used medicinally, ingestion can cause severe symptomssweating, nausea, vomiting, diarrhea, tremors, rapid heartbeat, confusion, convulsions, hypothermia, coma, or death

But it really stinks because smoking causes cancer, lung disease, heart diseaseand death!

For instance, this installment centering on a nightclub shooting includes guest star turns from a young Idris Elba (before HBOs The Wire) and Kerry Washington (long before ABCs Scandal)

This is because the sustained use of many drugs causes adaptation within the body that tends to lessen the drugs original effects over time, known as drug tolerance