The estimate of liver necrosis is rather small, less that 0.05% damage, and this may be sufficient to account for the elevation of ALT observed by Watkins et al.[38], and the absence of symptoms of liver disease after chronic usage
Spatial transcriptomics combined with single-cell RNA sequencing identified high expression levels of ferroptosis-related genes, including TFRC, NCO4, and SLC3A2, in granulosa cells of patients with ovarian senescence, while GPX4 expression was notably low (Lin et al., 2023)
To investigate the role of TRPV1-expressing neurons in oxazolone-induced colitis, mice were subcutaneously injected with capsaicin (50 mg/kg) twice on day 2 and 5 after birth
Physicians rarely look for environmental causes of disease, so they do not ask patients about current or past exposures