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In tumors, cancer cells preferentially use aerobic glycolysis, known as the Warburg effect, consuming excessive glucose to generate adenosine triphosphate (ATP) biosynthetic precursors while accumulating lactate ( Accumulating evidence shows that the acidic milieu caused by the build-up of lactate within the TME directly impedes immune cell activation and proliferation, and concomitantly potentiates the functionality of immunosuppressive cells via Kla

Hyperthyroidism is reported to decrease the HDL level and after treatment the HDL level increases [28] and these findings is consistent with our results

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Phytochemistry Reviews (2024)