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Accumulation of glutamine in the brain results in enhanced central nervous system uptake of tryptophan , which is converted into both neuroactive and neurotoxic metabolites, including serotonin and tryptamine

In one embodiment, the nanoparticles are suitable for use with hydrophobic active principles

Specifically, an initial reduction followed by a substantial increase in beta-endorphin levels was observed, a pattern that suggests DSIPs impact on the opioidergic system, potentially playing a role in stress alleviation or adaptation processes

The same study confirmed dose-dependent increases in GH without significant changes in other pituitary hormones (prolactin, TSH, LH, FSH, cortisol), supporting its selectivity for the GH axis