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These compounds are formed in organisms through external influences or metabolic pathways and irreversibly bind to DNA and proteins [4]

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Effect of diet-induced obesity or type 1 or type 2 diabetes on corneal nerves and peripheral neuropathy in C57Bl/6J mice

In addition, some authors investigated the risk associated with serum UA levels in a large cohort of patients with tauopathies (including subgroups with progressive supranuclear palsy, AD, and frontotemporal dementia) [222]