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Involvement of endoplasmic reticulum Ca2 + release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-beta peptide

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Therefore, IGF-I deprivation contributes to the progressive malnutrition in chronic liver disease patients, increasing the vulnerability of the liver to an inflammatory and oxidative microenvironment that increases the risk of cirrhosis development