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Moreover, wild-type TP53 appears to negatively control the mTOR pathway and the PPP, therefore governing fatty acid synthesis (175, 176)

GSH has been shown to exert an anti-influenza activity in vitro and in vivo, and depletion of GSH may have a fundamental role in COVID-19 and IAV infection susceptibility and disease severity 144,145

the main characteristic of ferroptosis is lipid peroxidation, which is a result of excessive ROS production [10]