Similarly, GLP-1 RAs, originally developed for the treatment of type 2 diabetes and obesity [128,129,130], have shown promising hepatoprotective and anti-inflammatory properties in preclinical models of alcohol-induced liver injury [131]
Finally, with multiple drug therapies now available for SCD and numerous novel therapies coming down the pipeline, further research into how to compare, combine, or sequence drug therapies is needed to establish data-driven guidelines for the treatment of complications in SCD
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IGF-1 LR3 has also shown promise in supporting fat metabolism, enhancing physical performance, and improving overall body composition