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ACKNOWLEDGEMENTS The authors extend their appreciation to Taif University, Saudi Arabia, for supporting this work through project number TU-DSPP-2024-175

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The founder's grandson, Patrick Reynolds, who watched from afar as his father passed away in his youth, sold all of his inherited Carmel stock and established a foundation called Tobacco-Free America (FSA) in 1986, and has been active as an anti-smoking activist in the United States

Visit the US Food and Drug Administration website to find out about the more than 7000 chemicals in both factory made and roll-your-own cigarettes