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Synthesis of GSH requires the consecutive action of two enzymes, -glutamylcysteine synthetase (-GCS) and GSH synthetase [3], (Fig

She exhibited low autonomic activity, diminished primitive reflexes, yellowish skin, muscular hypotonia, and poor peripheral blood circulation

Finally, the C-terminal Neh3 domain is another transactivation domain that recruits chromo-ATPase/helicase DNA-binding protein 6 (CHD6), functioning as an NRF2 transcriptional coactivator [153] (Fig

It can deliver glutathione to the cells efficiently, which improves the utilisation efficiency of glutathione in the body, allowing its physiological functions such as antioxidant and detoxification to be better performed