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A study showed that D2-like DRs agonist improves Th17/Treg imbalance by downregulating the expression of Th17-related pro-inflammatory cytokines but upregulating Treg-related anti-inflammatory cytokine expression (143), the effect of which can be suppressed by selective D2-like DRs antagonist

Particularly interesting may be gut peptides (6-8)

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Cell 130 , 10951107 (2007)