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Riboflavin and neurological disorders Several large observational studies in human cohorts have also associated B vitamins intake (e.g., vitamin B2, B9, and B12) and other dietary habits with mental health, particularly in adolescent girls (Japanese cross-sectional study, n = 3450) 59 , and women who suffer from postpartum depression (cross-sectional study, n = 344) 28 or premenstrual syndrome (PMS) (case-control study, n = 3025) 60

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No significant organ toxicity has been reported in acute or subacute animal studies, and the peptide has not demonstrated mutagenic activity in standard assays