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4,27,28 Clinically, this translates to deterioration in the quality of life of the patient presenting with pain

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When reproducible physiology and biochemistry persist across years, modalities, and care settings, the question stops being is anything wrong? and becomes a governance one: Who owns the trigger for reevaluation when signals persist but dont fit a textbook pathway and where is that ownership documented so cases dont stall between handoffs

I was looking at DNA double-stranded breaks in peripheral blood, mononuclear cells from participants in clinical trials where we had obese people that, uh, were given a micronutrient-rich bar developed by Bruce and his colleagues Gordon: Mm-hmm