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GHK-Cu: The Copper Peptide That Rewires Gene Expression for Tissue Repair GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring tripeptide first isolated in 1973 by biochemist Loren Pickart, who observed that plasma from younger individuals stimulated regenerative processes more effectively than plasma from older adults.21 Tracing this activity to a small copper-binding peptide, Pickart launched over five decades of research into a molecule with an unusually broad biological profile: it stimulates blood vessel and nerve outgrowth, increases collagen, elastin, and glycosaminoglycan synthesis, and supports dermal fibroblast function.22 The Gene-Expression Story What distinguishes GHK-Cu is the scale of its gene-regulatory effects

But I'm really excited to talk with Peter today because we have a lot of overlap in our interest in longevity, particularly the role of diet, nutrition, and other lifestyle factors like sleep, exercise, stress in longevity

Pejman Katiraei is a board-certified pediatrician who has completed two fellowships in integrative medicine and has over a decade of clinical experience helping children with severe learning and behavioral challenges

A role for proapoptotic BID in the DNA-damage response