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A compromised intestinal lining allows bacterial endotoxins into systemic circulation, driving inflammatory cytokine production that worsens insulin resistance and ovarian function

Edited by Boris Zhivotovsky Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

Currently, the most complete study associated to mitochondrial alterations corresponds to our findings [128]