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Furthermore, it has been found that modulation of the Nrf2 signalling pathway by triterpenoids compounds results in a significant increase in survival in the SOD1 G93A mouse model of ALS, thereby indicating that activation of Nrf2 has a neuroprotective effect [268]

[73,74] Other peptides derived from histone proteins have shown similar effects and have been investigated as therapeutic candidates in SLE, [75, 76, 77] including the phosphorylated spliceosomal epitope peptide P140, which represses B cell differentiation and protects against murine lupus

10.1152/physrev.00015.2009 39 MadlalaH

5 mg Vitamin B3 (niacinamide)