These include: The severity of B12 deficiency The presence of underlying health conditions Genetic variations affecting B12 metabolism The duration of supplementation Knowing these factors helps tailor the dose to meet individual needs, ensuring the best results
Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8
Red flags include no intake form, no mention of a supervising physician, aggressive upselling during the appointment, and providers who cannot explain what form of B12 they are injecting or why
There are also instances where patients come in on a circumstantial basis if they: need an immune boost, want a hangover cure, are feeling under the weather, or are preparing for, or recovering from, a big athletic event like a marathon or other athletic competition