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Impact of COVID-19 on mitochondrial-based immunity in aging and age-related diseases

It is found that when blood flow exhibits disturbed or oscillatory shear stress, MerTK expression is suppressed in human aortic ECs (HAECs), affecting their ability to phagocytose apoptotic cells

Particularly in different pathophysiological scenarios, mitophagy has been confirmed to exert both protective and detrimental effects, and the underlying mechanisms of this bidirectional regulatory effect have not yet been fully elucidated

10.20944/preprints201810.0166.v1 [DOI] [PMC free article] [PubMed] [Google Scholar] 179.Kang Y, Song Y, Luo Y, Song J, Li C, Yang S, et al