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DZN was administered after hormonal stimulation with PMSG and hCG, and it significantly altered the expression of StAR , an important gene in steroidogenesis, in a time-dependent manner and reduced CL diameter compared to that in the control group

Injectable GHK-Cu was in Category 2 the more restrictive category for substances with "significant safety concerns." Its removal from Category 2 is the more positive development, as it signals the FDA no longer considers injectable GHK-Cu to carry the safety risk level that warranted Category 2 placement

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