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Here we find increased proportion of pro-inflammatory and mesenchymal fibroblast subpopulations and senescent fibroblasts, and enhanced expression of senescence-associated secretory phenotype genes using single-cell RNA sequencing analysis, as well as elevated p16 protein and more -galactosidase-positive cells in keloids

Activation leads to stabilization of -catenin and transcription of downstream targets associated with follicle growth and tissue repair

Current Pharmaceutical Design : Studies focus on its regenerative properties linked to actin upregulation, facilitating faster healing of injuries

It helps fix tendons, ligaments, muscles, bones and even the wall of the gut