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HL and XZ put forward a lot of invaluable opinions for revision and finalized the manuscript

Since BPC-157 is not an approved therapeutic agent in any country, there is no basis for granting a TUE for this substance

Whilst the specific molecular structure of this pathway is less understood than the pore pathway, it is thought to be regulated by occludin, tricellulin, ZO-1, and perijunctional actomyosin [19, 33], although there is evidence that alterations in tricellulin expression may affect permeability of this pathway [34]

Originally identified in human plasma, GHK-Cu is composed of the amino acid sequence glycyl-L-histidyl-L-lysine bound to copper ions