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Providers must establish baseline blood pressure and resting heart rate before initiating therapy

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Activation of 3-AR via Gs cAMP PKA phosphorylation of hormone-sensitive lipase (HSL) leads to: Splitting of triglycerides into free fatty acids + glycerol Release of fatty acids from adipose tissue into the blood Increased oxidation of fatty acids in mitochondria (muscle, liver) Heffernan et al

Table S2: The effects of adaptogens on canonical pathways are commonly involved in regulating adaptive stress response signaling, adapted from References [66,67]