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To generate 3-methylindolyl glutathionyl disulfide (ISSG), bis -(3-indolemethyl) disulfide (ISSI) was synthesized as described ( 2 O 2 , and the reaction incubated for 16 h at 22C

10.3390/nu12082227 90 ShannonO

Nutrients 2023;15:4480

It has been shown that low-frequency recombination with silent tpsC cassettes, which share sequence similarity with the central region of tpsA but show an entirely different 3-terminal sequence, may introduce different toxic modules at the variable C-terminus of meningococcal TpsA ( tpsC cassettes and the cognate IORFs could confer increased plasticity to a genomic region that appears to be involved in the evolution of virulence in meningococcus