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Overexpression studies have confirmed the role of DHAR in maintaining a high tissue ascorbate redox state, and have highlighted the roles of GSH-dependent ascorbate pools in a number of physiological responses, eg, the control of stomatal closure (Chen et al., 2003)

Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo

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