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doi: 10.3389/fphar.2022.1034870 Received 02 September 2022 Accepted 24 November 2022 Published 02 December 2022 Volume 13 - 2022 Edited by Karl Tsim, Hong Kong University of Science and Technology, Hong Kong SAR, China Reviewed by Hoi Huen Chan, Hong Kong Polytechnic University, Hong Kong SAR, China Prabhu Balan, Massey University, New Zealand Ik-Hyun Cho, Kyung Hee University, South Korea Updates Copyright 2022 Liu, Hu, Mao, Liu, He, Hui, Yang, Qu, Lian, Duan, Dong, Pan, Liu, He, Li and Wang

Interoception and the neuro-immune system In what follows, we will see that in PAIS, the bidirectional exchange of information between the brain and the other organs is deeply perturbed, in other words interoception no longer works properly